Thoracic Research and Practice
Original Article

Risk Factors and Clinical Determinants in Bronchiolitis of Infancy


Necmettin Erbakan University Meram Faculty of Medicine, Department of Pediatrics, Division of Pediatric Pulmonology, Konya, Turkey


Baskent University Konya Hospital, Department of Pediatrics, Division of Pediatric Allergy and Immunology, Konya, Turkey


Necmettin Erbakan University Meram Faculty of Medicine, Department of Microbiology, Konya, Turkey

Thorac Res Pract 2020; 21: 156-162
DOI: 10.5152/TurkThoracJ.2019.180168
Read: 1569 Downloads: 634 Published: 13 September 2019

OBJECTIVES: The aims of this study was to demonstrate the viral pathogens, to evaluate the clinical prognosis, risk factors for recurrence, severity of acute viral bronchiolitis episodes among pediatric patients.

MATERIALS AND METHODS: Our study included 101 children aged between 2 months and 2 years diagnosed with clinical bronchiolitis between September 2011 and April 2012. The demographics and clinical, laboratory, and radiological results of the patients were recorded. Nasopharyngeal swab samples were collected and analyzed through polymerase chain reaction (PCR) method. The patients were followed up for at least one year for new episodes, existence of wheezing, frequency of pulmonary infections, and progression of asthma.

RESULTS: In half of the patients, determinants were indicated through the PCR method, with the most frequent being respiratory syncytial virus (44%). The frequency of bronchiolitis was higher in prematures (p<0.005). There was a relationship between crowded family structure and the existence of wheezing (p=0.003), increased recurrence (p=0.014), and need for inhaler treatment (p=0.014). The frequency was higher in patients living in urban cities (p<0.001), in houses with heating stoves (p=0.001), and in houses with smokers (p=0.001). Patients living in houses with heating stoves had more severe episodes (p=0.018). Recurrent wheezing and the need for regular inhaler usage were positively correlated with high API scores (p=0.008 and p=0.002, respectively).

CONCLUSION: Prematurity, exposure to smoking, living in a crowded house with heating stoves, and an urban life are the risk factors for frequent bronchiolitis. The API can be used to predict the recurrence of bronchiolitis.

Cite this article as: Atay Ö, Pekcan S, Göktürk B, Özdemir M. Risk factors and clinical determinants in bronchiolitis. Turk Thorac J 2020; 21(3): 156-62.

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