Lipid Profile in Patients with Chronic Obstructive Pulmonary Disease

The aim of this study was to evaluate the serum level of total cho­lesterol, triglycerides (TG), low density lipoproteins (LDL), very low density lipoproteins (VLDL), high density lipoproteins (HDL), apolipoprotein A [Apo(a)], apoprotein B [Apo(b)] and lipoprotein [Lp(a)] in chronic obstructive pulmonary disease (COPD) patients. Twenty patients with COPD and 20 healthy controls were recruited to the study. Total cholesterol, HDL and TG levels were determined with ILAB 1800 Chemistry Analyzer using ILAB test Reagents. LDL concentration was calculated using the Friedewald Equation. VLDL concentration was calculated using VLDL-choles- terol=triglyceride/5 formula. Apo(a), Apo(b), Lp(a) concentrations were measured with the Beckman-Array 360 Nephelometers using Beckman Array® system reagents. HDL level was 53.45±16.39 mg/dl in COPD patients and 3Ğ.65+5.33mg/dl in controls (p=0.00). No relationship was observed between the increased HDL levels of the patients, the blood gas and respiratory function tests (RFT), or other parameters. It was concluded that COPD patients do not show an athero- genetic lipid pattern and that the increased HDL levels might be related to the drugs used by these patients.