Behçet’s disease is a rare form of vasculitis of obscure aetiology. We report two cases of Behçet’s disease with intracardiac thrombus and pulmonary artery aneurysm occurring together. The clinical characteristics of the two patients, one male, one female, were analysed retrospectively. The male patient (age:27) was admitted for pleuritic chest pain and the female patient (age:35) for high fever of unknown origin. Both patients had multiple subpleural nodules, right-sided cardiac thrombi, and bilateral pulmonary artery aneurysms. In the female patient the intracardiac thrombus was removed by surgery but she died after six months as a result of a massive haemoptysis. The male patient was treated with immunosuppressive drugs, is still alive and doing well.