We report a 46 year-old male patient who admitted to our clinic with massive hemoptysis, epistaxis, and generalized petechiae. A diagnosis of immune thrombocytopenic purpura was established according to clinical and laboratory findings including bone marrow aspiration. Intravenous immune globulin (IVIg) and methylprednisolone therapy were started. In the folow-up, the patient was found to have clinical, microbiological and radiological evidence of active pulmonary tuberculosis. No platelet response was achieved to IVIG and methylprednisolone therapy and antituberculous drugs were given. By the end of the first week, hemoptysis, epistaxis, and generalized petechiae resolved and platelet counts returned normal levels after four-weeks of treatment.