Thoracic Research and Practice
Original Article

Comparison of Solid (Lowenstein-Jensen) and Liquid (MGIT: Mycobacteria Growth Indicator Tube) Media for Early Diagnosis of Pulmonary Tuberculosis


Atatürk Göğüs Hastalıkları ve Göğüs Cerrahisi Eğitim ve Araştırma Hastanesi, Ankara


Refik Saydam Hıfzıssıhha Merkez Başkanlığı Tüberküloz Referans Laboratuvarı, Ankara


Hacettepe Üniversitesi, Fen Fakültesi, istatistik Bölümü, Ankara

Thorac Res Pract 2003; 4: Toraks Dergisi 138-142
Read: 931 Downloads: 482 Published: 18 July 2019


Mycobacteria Growth Indicator Tube System (MGIT) is a new liquid medium system developed of mycobacteria forculture and susceptibility testing has been developed. Between November 2000 and May 2001, sputum samples of 22 smear negative pulmonary tuberculosis patients were cultured in Löwenstein – Jensen (L-J) solid media and MGIT. The rate of recovery of acid-fast bacilli (AFB) and the mean time of their detection from sputum of these two media were compared. Rates of recovery of mycobacteria were 31.8% and 27.2% for MGIT and L-J media, respectively. The mean time of detection were 13.28 days for MGIT, whereas 27.33 days for L-J media. While there is no statistically significant difference for the rate of recovery of AFB between two medias (p=0.9968; >0.05), the mean time of detection for MGIT was statistically shorter than that for LJ (p=0.028; <0.05). As a conclusion MGIT is a suitable, rapid, sensitive, efficient and nonradiometric method for the recovery of mycobacteria. We believe that it may be used routinely with LJ.

EISSN 2979-9139