Thoracic Research and Practice

Angiotensin-Converting Enzyme Inhibitors Induce Cough


Department of Chest Diseases, Division of Immunology and Allergy, Erciyes University School of Medicine, Kayseri, Turkey

Thorac Res Pract 2019; 20: 36-42
DOI: 10.5152/TurkThoracJ.2018.18014
Read: 6164 Downloads: 1069 Published: 18 July 2019



Angiotensin-converting enzyme inhibitors (ACE-I) are widely used in diseases, such as hypertension, congestive heart failure, and myocardial infarction. Although these drugs are well tolerated, one out of five patients discontinues ACE-I due to drug side effects, mainly chronic cough. However, the pathogenesis of ACE-I-induced cough remains controversial and requires further study. In this review, the mechanisms that are suggested in ACE-I-induced cough pathophysiology will be discussed in detail in light of the current literature.


Cite this article as: Yılmaz İ. Angiotensin-Converting Enzyme Inhibitors Induce Cough. Turk Thorac J 2019; 20(1): 36-42.

EISSN 2979-9139