Diagnosis of extrapulmonary tuberculosis (TB) is often difficult. A case with diagnosis of abdominal and possible cranial, mediastinal, pulmonary and ovarian TB was treated with combined chemotherapy of streptomycin, ethambutol, rifampin, and pyrazinamide. She made a good recovery with almost complete resolution of the radiographic appearances after a six- month therapy. Diagnosis of extrapulmonary TB can be easily missed unless the disease is suspected. Solid lesions in multiple localizations, especially those imitating tumor metastasis, must alert clinicians to extrapulmonary TB.