Pulmonary alveolar proteinosis (PAP) is a rare disease characterised by diffuse aacumulation of eosinophilic periodic acid-shiff (PAS) positive phospholipid materials within alveoli. The accumulation of this material is due to an increased secretion or a decreased clearance from the alveoli. Whole lung lavage is the most effective and safe method of treatment.idiopathic pulmonary alveolar proteinosis The certain diagnosis of PAP was made by transbronchial biopsy (TBB) and bronchoalveolar lavage (BAL).He was treated with whole lung lavage. The procedure was performed three times. Marked clinical and laboratory improvement was achieved besides a minimally radiographic regression.