We report an unusual case of endobronchial inflammatory polyp in a 36-year-old woman who presented with a history of dyspnea, intermittent cough, wheeze and recurrent infections. She had been treated for bronchial asthma for three years but never recovered. The right lower lobe was totally atelectatic at computed tomography of the thorax. Bronchoscopic biopsy taken from the obstructive lesion did not lead to specific diagnosis. An exploratory surgical resection was performed and a diagnosis of endobronchial inflammatory polyp was made histopathologically. The etiology could not be identified. Six months after the resection, the patient fully recovered and did not suffer from asthmatic complaints.