Abstract

A 17 –year-old HIV-negative male patient with a PPD induration of 5 mm and presenting with the com - plaints of weight loss, fever, thoracic and abdominal pain, and cough of 8-month duration was considered to have malignancy (particularly lymphoma) due to diffuse mediastinal, hilar, abdominal and axillary lym - phadenopathies, multiple pulmonary nodules, hepatosplenomegaly and hypodense multiple splenic lesions. However, endobronchial biopsy and excisional biopsy of the axillary lymphadenopathy revealed tuberculosis (TB). AntiTB treatment [ 2 months of (streptomycin + isoniazid + morphozinamide + rifampicin) and 1 month of (ethambutol + isoniazid + morphozinamide + rifampicin)] resulted in marked improvement in clin - ical radiological and laboratory findings in 3 months. Treatment was completed in 9 months with a 6-month maintenance of (isoniazid + rifampicin). HIV test was found to be negative, and PPD induration was 10 mm in the 9th month of the antiTB treatment. The case was presented because of its extraordinary and diffuse involvement mimicking malignancy, and was discussed in the light of relevant literature.