Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods
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Original Article
VOLUME: 23 ISSUE: 4
P: 261 - 267
July 2022

Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods

Turk Thorac J 2022;23(4):261-267
1. Department of Chest Medicine, Mansoura University, Mansoura, Egypt
2. Department of Radio-Dignosis and Interventional Radiology, Mansoura University, Mansoura, Egypt
3. Department of Public Health, Mansoura University, Faculty of Medicine, Mansoura, Egypt
4. Department of Rheumatology & Immunology, Mansoura University, Mansoura, Egypt
No information available.
No information available
Accepted Date: 10.05.2022
Online Date: 01.07.2022
Publish Date: 10.05.2022
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Abstract

OBJECTIVE:

 Interstitial lung disease is the most frequent lung symptom of rheumatoid arthritis and is a significant contributor to morbid- ity. As a result, the target of this research was to measure the frequency of radiological and functional abnormalities in rheumatoid arthritis patients who did not have any respiratory symptoms.

MATERIAL AND METHODS:

 This study consists of 30 patients diagnosed with rheumatoid arthritis. All involved cases were exposed to entire history taking and clinical examination. All patients were examined by high-resolution computed tomography and pulmonary function tests.

RESULTS:

 According to the computed tomography visual score, 73.3% showed interstitial lung disease. The most common abnormalities were reticular patterns (46.7%) followed by nodular patterns (40%) and septal lines (23.3%). However, 36% of the patients had a normal pulmonary function, while 32% had a small airway affection, 20% had restrictive lung disease, and 12% had obstructive lung disease. A significant association was found between supine expiratory volume and computed tomography visual score. Results showed no associa- tion between interstitial lung disease and all lung function test parameters.

CONCLUSION:

 Subclinical interstitial lung disease is frequent among rheumatoid arthritis patents. A combination of pulmonary func- tion tests with computed tomography is essential to enhance the recognition of subclinical interstitial lung disease as normal pulmonary function alone cannot exclude its presence.

Cite this article as:

 Wagih Abdelwahab H, Shalabi NM, Mohamed Rashad Ghoneim M, et al. Screening for subclinical interstitial lung disease in rheumatoid arthritis patients: Functional and radiological methods. Turk Thorac J. 2022;23(4):261-267.

Keywords:
Rheumatoid arthritis, subclinical interstitial lung disease, pulmonary function test