Abstract
A 19-year-old man is reported who had underwent bone marrow transplantation (BMT) for acute myelogenous leukemia developed respiratory complaints of productive cough and progressive dyspnea at post-transplant day 278 and was hospitalised. Chest-x-ray and high resolution computed tomogaphy (HRCT) revealed cylindirical bronchiectasis. Pathologic examination of transbronchial biopsy was consistent with chronic graft-versus-host disease(CGVHD). The patient had no history of respiratoiy disease or any other condition that could cause bronchiectasis other than CGVHD. Bronchiectasis can be considered as an early predictor of CGVHD and its early diagnosis by HRCT in suspicion of GVHD after BMT may lead to early re-evaluation of treatment.
Keywords:
Chronic graft-versus-host disease, Bronchiectasis, Allogeneic bone marrow transplantation, High resolution computed tomography