Abstract

Pleural effusion, diffuse endobronchial mucosal involvement and distal airway obstruction were observed in a 50-year-old woman. Chest X-ray revealed mediastinal lymphadenopathy and diffuse parenchymal infiltrates. Extensive extrapulmonary involvement was not present. Both transbronchial lung biopsy and pleural biopsy demonstrated non-caseating granulomas consistent with sarcoidosis. The patient was given prednisone which was continued for 18 months in gradually decreasing doses. This treatment resulted in marked improvement of bron­choscopic findings. The simultaneous presence of pleural effu­sion and endobronchial involvement in the same patient is a rare occurrence in sarcoidosis.