A Case of Sarcoidosis Presenting With Diffuse Endobronchial Involvement and Pleural Effusion
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Case report

A Case of Sarcoidosis Presenting With Diffuse Endobronchial Involvement and Pleural Effusion

Thorac Res Pract 2002;3(3):122-126
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Abstract

Pleural effusion, diffuse endobronchial mucosal involvement and distal airway obstruction were observed in a 50-year-old woman. Chest X-ray revealed mediastinal lymphadenopathy and diffuse parenchymal infiltrates. Extensive extrapulmonary involvement was not present. Both transbronchial lung biopsy and pleural biopsy demonstrated non-caseating granulomas consistent with sarcoidosis. The patient was given prednisone which was continued for 18 months in gradually decreasing doses. This treatment resulted in marked improvement of bron­choscopic findings. The simultaneous presence of pleural effu­sion and endobronchial involvement in the same patient is a rare occurrence in sarcoidosis.

Keywords: pleural effusion, non-caseating granuloma, endobronchial involvement